5x More Male DNA

SpermX™ GenSpin™

Solve more sexual assault cases.
  • 80% Sperm Recovery: Capture what traditional “pellet and decant” methods lose. Removing the swab during traditional processing can lead to losses of up to 80% of sperm DNA.
  • Superior Purity: Engineered for a cleaner male fraction with significantly less female DNA interference.
  • Novel Filtration Technology: Our unique filter captures sperm cells from the lysis buffer, replacing decades-old pelleting techniques. The device holds the sperm cells in a special membrane matrix.
  • SPECIAL 50% Off: Validate the results in your own lab.
    Get a 20-reaction sample kit for just $200 through March 31, 2026.

    Peer-Reviewed Interlaboratory Paper

    “Interlaboratory Comparison of SpermX™ and Conventional Differential Extractions Indicated High Male DNA Recovery by the SpermX Method” December 2023 Forensic Sciences 3(4):592-610 DOI:10.3390/forensicsci3040043
  • 7-Fold Allele Increase: SpermX yielded a seven-fold increase in the recovery of unshared male alleles compared to standard DE.
  • Success with 25 Cells: The system provided CODIS-uploadable profiles from as few as 25 sperm cells, where traditional protocols failed.
  • Higher Probabilistic Certainty: Likelihood Ratios (LRs) were higher by 2 to 23 orders of magnitude than conventional methods.
  • “In our hands the SpermX non-polymer membrane demonstrated excellent performance with semen-containing vaginal swabs, delivering higher DNA recovery from sperm fractions compared to our standard differential extraction (DE) method and showing less female carry over. Its most impressive advantage was seen in some low-sperm samples, where male DNA was recovered with Sperm X but not with our DE. If I was running a casework lab, I would definitely investigate its potential for routine use.”

    Jack Ballantyne, PhD
    Professor, Department of Chemistry, Director, National Center for Forensic Science

    Casework Implementation & CODIS Success

    SpermX with GenSpin Outperforms the DNase Differential Extraction Method
    From DNA Solutions
  • 30% Increase in Profiles: Implementation at DNA Solutions resulted in a ~30% increase in CODIS-eligible profiles from Y-screen positive cases.
  • Enhanced Evidentiary Value: Data demonstrates improved recovery of probative male DNA in challenging sexual assault evidence.
  • Sustained Performance: Casework analysis shows measurable and sustained improvement in generating CODIS-eligible profiles over time.
  • Head-to-Head Sensitivity vs. EZ1

    Differential Extraction Sensitivity Study From Palm Beach County Sheriff’s Office
  • 26x Higher Yield: Yielded up to 26x higher Y-target DNA concentrations than standard automated protocols.
  • Reliable Allele Recovery: Preserved >89% of expected alleles at 1:100 dilutions, while traditional methods dropped below 50% recovery after 1:25.
  • Superior Sensitivity: Consistently outperformed the lab’s current differential extraction method in both DNA recovery and allele detection.
  • “The implementation of SpermX™ GenSpin™ led to approximately a 30% increase in the number of eligible male DNA profiles for CODIS from Y screen positive samples, even those with low male DNA input. This data confirms that SpermX consistently improves performance, making it a valuable enhancement to our sexual assault evidence workflow.”

    Huma Nasir, MS, ABC-MB
    Forensics Lab Director & Assistant Technical Leader, DNA Solutions